VAM Disease

What is VAM Disease?

VAM Disease (Venous and Arterial Mixed Disease) occurs when a patient has both peripheral artery disease (PAD) and chronic venous insufficiency (CVI). PAD restricts oxygen-rich blood from flowing to the legs, while venous disease prevents blood from flowing back to the heart efficiently. These two conditions often coexist but are rarely diagnosed or treated together, leading to incomplete care and persistent symptoms.

At 360 Vascular Institute, we specialize in identifying and treating both components, offering a complete solution for patients who have been underserved by fragmented care.

Incidence of VAM Disease

VAM Disease is more common than most people — and even many healthcare providers — realize. Many patients with PAD have underlying venous disease and vice versa. When only one issue is addressed, patients may continue to struggle with leg pain, swelling, skin changes, or wounds that won’t heal. We frequently diagnose VAM Disease in patients who’ve had prior treatments with limited success because the full picture wasn’t addressed.

Is VAM Disease Hereditary?

While VAM Disease is not directly inherited, many of its contributing risk factors can be. Conditions like diabetes, high blood pressure, and vein disorders often run in families. The development of both arterial and venous disease is usually the result of a combination of genetic predisposition, lifestyle, and anatomical factors.

Risk Factors for VAM Disease

Several overlapping risk factors increase the chances of developing both arterial and venous circulation problems. These include:

  • Age over 50

  • Smoking history

  • Diabetes or elevated cholesterol

  • Obesity or sedentary lifestyle

  • Family history of vascular disease

  • Varicose veins or previous blood clots

  • Jobs requiring long hours of sitting or standing

Signs and Symptoms of VAM Disease

VAM Disease often causes a mix of symptoms, which can make diagnosis difficult. Common signs include:

  • Cramping or pain when walking (claudication)

  • Swelling in the legs or ankles

  • Rest pain or numbness in the feet

  • Skin discoloration near the lower legs

  • Visible varicose or spider veins

  • Heavy, tired-feeling legs

  • Open sores or ulcers that are slow to heal

  • Hardening, thinning, or itching of the skin

If you’ve already been treated for PAD or venous disease but still experience symptoms, you may have VAM Disease.

Diagnosis of VAM Disease

At 360 Vascular Institute, diagnosis starts with a thorough evaluation. Our state-of-the-art imaging and diagnostic testing are performed right here in our office — no need to visit multiple locations. This allows us to assess both arterial blockages and venous reflux in one setting and pinpoint the true source of your symptoms.

Treatment of VAM Disease

360 Vascular Institute is the region’s only outpatient vascular and interventional radiology center with the expertise to recognize, diagnose, and treat VAM Disease effectively. Our care is minimally invasive, does not require a hospital stay or surgical incisions, and offers a faster recovery than traditional open surgery. Due to the complexity in diagnosing and treating VAM Disease, every patient (including those without VAM Disease) is seen by Dr. Sudi to come up with a personalized treatment plan.

Importance of Seeing a Vascular Specialist

If you suspect that you have VAM Disease, it’s essential to consult with a vascular specialist with expertise in BOTH arterial and venous disease, as many vascular specialists only treat one condition. An experienced vascular specialist can:

  • Provide an accurate diagnosis through appropriate imaging and testing.
  • Offer a tailored treatment plan to manage symptoms and prevent complications.
  • Monitor the progress of your condition and adjust treatments as needed.
  • Ensure proper long-term care and management to maintain the best possible circulation and quality of life.

Early diagnosis and intervention can help reduce the risks of complications and improve your overall vascular health.

Learn More About VAM Disease

Read more in the Patient Education Library, where Dr. Sudi explains Venous and Arterial Mixed disease and why both problems are often present together.

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